Superiority
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air.The most professional forwarder would be recommanded for you.
5. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.Adhering to the principle of customer first conviction.we will provide the best and the most sincere services as possible as we can.
Details
99% Purity Aromatase Inhibitor Lentaron Formestane For Anti Cancer
|
Name |
Formestane
|
|
CAS |
566-48-3
|
|
MF |
C19H26O3
|
|
MW |
302.41
|
|
Purity |
>99%
|
|
Appearance |
White Powder
|
|
MP |
199-202°C
|
|
Certification |
ISO 9001, USP, BP
|
|
Suitable for |
Adult
|
|
Standard |
Enterprise Standard
|
|
Usage |
An antitumor drug. An aromatase inhibitor
|
|
Dosage |
250mg,1 time every two weeks,as the arm deep intramuscular injection.
|
|
Packing |
Discreet packing ways as your requirement, 100% go through
|
|
Storage |
Store in cool and dry area and keep away from direct sunlight
|
Description:
A. Formestanes is a synthetic steroidal substance with antineoplastic activity. Formestanes binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.
B. Formestanes is a drug that has been previously used in breast cancer treatment. Like most drugs which have some sort of phsyique usage, athletes eventually get a hold of it. Formestanes is currently one of the best legal anti-estrogens out there. It is classified as an irreversible arromatase inhibitor, meaning, it destroys the aromatase enzyme.
Applications:
Formestane is a second generation, irreversible, steroidal aromatase inhibitor. It inhibits the aromatase enzyme responsible for converting androgens to estrogens, thereby preventing estrogen production. Breast cancer may be estrogen sensitive or insensitive. A majority of breast cancers are estrogen sensitive. Estrogen sensitive breast cancer cells depend on estrogen for viability. Thus removal of estrogen from the body can be an effective treatment for hormone sensitive breast cancers. Formestane has been targeted specifically for the treatment of postmenopausal women. Unlike premenopausal women who produce most estrogen in the ovaries, postmenopausal women produce most estrogen in peripheral tissues with the help of the aromatase enzyme.
Formestane, an aromatase inhibitor, can thus help to decrease the local production of estrogen by blocking the aromatase enzyme in peripheral tissues (ie. Adispose tissue of the breast) to treat hormone sensitive breast cancer.
Currently, formestane (categorized as an anti-estrogenic agent) is prohibited from use in sports in accordance to the regulations of the World Anti-Doping Agency. It is not US FDA approved, and the intramuscular injection form of formestane (Lentaron) which was approved in Europe has been withdrawn.
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.
Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosteron, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.
Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.
China (Mainland)