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Country: China (Mainland)
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CAS NO.54-31-9
Enterprise standard(1-10)GramEnterprise standard(11-100)Gram
99% Purity pharmaceutical material Furosemide for antihypertensive
Synonyms |
LABOTESTBB LT00244801;FUROSEMID;FUROSEMIDE; FRUSEMIDE |
CAS NO |
54-31-9 |
MF |
C12H11ClN2O5S |
MW |
330.74 |
Purity |
99% |
Appearance |
white to light yellow crystal powder |
Certification |
USP, SGS, ISO9001 |
Standard |
USP |
Usage |
Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic. |
Packing |
Discreet packing ways as your requirement, 100% go through |
Storage |
Store in cool and dry area and keep away from direct sunlight |
Application:
Furosemide, is a class of efficient sulfonamide diuretics acting on the medullary loop of the ascending
branch of the medulla,it has a strong and short-term diuretic effect,which can increase the excretion of
water, sodium, chloride, potassium, calcium, magnesium, phosphate and so on. It Mainly inhibits Na +
and Cl- reabsorption in medullary and cortex of the medullary loop ascending branch crude segment ,
it can promote the excretion of sodium, chloride and potassium and affect the formation of renal
medullary high osmotic pressure,it can interfer the process of concentration and dilution of urine, and it
can increase urine output.
This product can inhibit the activity of prostaglandin decomposition enzyme ,make the content of
prostaglandin E2 increase,it has effect on expansion of blood vessels, it also plays a role in the
proximal tubule, glomerular filtration,it can increase renal blood flow,and adjust renal blood flow
distribution,and reduce blood flow so that the cortex surface blood flow increases,it promotes diuresis,
its effect is fast and strong, it is used for other diuretics invalid cases. Clinically it is used for the
treatment of cardiac edema, renal edema, cirrhosis ascitic fluid, peripheral edema caused by
dysfunction or vascular disorders , and it may contribute to an upper urinary tract stones excretion.
Administration intravenously can treat brain edema, it also can accelerate the excretion of toxic
substances in cerebral edema in poisoning .
Uses:
The diuretic effect of this product is a strong and short,it is a potent diuretic for the treatment of edema
caused by heart, liver, kidney and other diseases, in particular, the base cases which other diuretics
are invalid to;it can be used to treat acute pulmonary edema, brain edema , acute renal failure and
high blood pressure and other diseases; in combination with fluid infusion, the product can promote
poison excretion. Rat oral LD50 is 2600-2820mg / kg.
Usage:
1.Diuretic, antihypertensive
2.Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic.
3.This compound belongs to the aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.