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CAS NO.22832-87-7
USP(1-10)GramUSP(11-100)Gram
Synonyms |
1h-imidazole; daktacort |
CAS NO |
22832-87-7 |
MF |
C18H15Cl4N3O4 |
MW |
479.14 |
Purity |
99% |
Appearance |
White crystalline powder |
Certification |
ISO 9001, USP, BP |
Standard |
USP |
Usage |
An antifungal agent that inhibits platelet cyclooxygenase |
Packing |
Discreet packing ways as your requirement, 100% go through
|
Storage |
Store in cool and dry area and keep away from direct sunlight |
Miconazole nitrate is a kind of artificially synthetic 1-phenylethyl imidazole derivatives and belongs to
imidazole-class broad-spectrum antifungal drug. It is a commonly used drug for treating skin ringworm
without containing hormones and without side effects. Its main active ingredient is miconazole. However,
miconazole nitrate is now seldom used in China. Its antibacterial spectrum, antibacterial activity and
mechanism of action are all similar with clotrimazole. It can be used as a substitute drug when the
treatment of amphotericin in deep fungal infection is invalid. It is suitable for treating the systemic,
disseminated infection caused by some kinds of fungus.
Test Items | Specification |
Test Results |
|
Appearance | White or Almost white powder |
Complies |
|
Identification | IR |
Similar to standard |
Complies |
Appearance of Solution |
The solution is clear and not more intensely cloured than reference solutions |
Complies | |
Solubility |
Very slightly soluble in water; soluble in methanol ; slightly soluble in alcohol |
Complies | |
Angle of optical rotation |
-0.1o~+0.1o | Complies | |
Related Substances | Each Impurity |
≤0.25% |
0.18% |
Total Impurity |
≤0.5% |
0.25% | |
Melting Point |
163~167ºC |
164.5ºC | |
Loss on Drying |
≤0.5% | 0.32% | |
Residue on Ignition |
≤0.1% | 0.01% | |
Assay (on dry basis) |
98.0~102.0% | 99.38% |