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CAS NO.144701-48-4
Pharmaceutical grade(1-10)GramPharmaceutical grade(11-100)Gram
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High purity pharmaceutical material Telmisartan for Hypertension
Synonyms |
PRITOR;MICARDIS |
CAS NO |
144701-48-4 |
MF |
C33H30N4O2 |
MW |
514.63 |
Purity |
99% |
Appearance |
White or off white crystalline powder |
Certification |
ISO 9001, USP, BP |
Standard |
Pharmaceutical Grade |
Usage |
It can be used as anti-hypertensive drugs and vasodilator hormone antagonist. |
Packing |
Discreet packing ways as your requirement, 100% go through |
Storage |
Store in cool and dry area and keep away from direct sunlight. |
Usage:
Used alone or in combination with other classes of antihypertensives for the treatment of hypertension.
Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes
mellitus,as well as the treatment of congestive heart.
Description:
Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which
includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand).
Angiotensin,formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful
chemical that attaches to angiotensin receptors found in many tissues but primarily on muscle cells of
blood vessels. Angiotensin's attachment to the receptors causes muscle cells to shorten and narrow
the blood vessels (vasoconstrict), which leads to an increase in blood pressure (hypertension).
Telmisartan blocks the angiotensin receptor. By blocking the action of angiotensin, telmisartan widens
blood vessels (vasodilate) and reduces blood pressure.
Application:
Telmisartan belongs to a class of drugs called angiotensin receptor blockers. A class of drugs is a
group of medications that work in a similar way. They're often used to treat similar conditions.
Telmisartan works by blocking the effect of angiotensin. This makes your blood vessels relax more. it
also allows your kidney to get rid of excess water and salt. This helps lower your blood pressure.
To reduce risk of atherosclerosis, cardiovascular disease, or stroke where risk is only moderate in the
first place, I suggest a dose from 20 to 40 mg taken orally once per day. Dosing would be the same
where the interest is slowing loss of brain function with age, or potentially improving brain function.
For possible improvement in fat loss, particularly of visceral fat, or improvement of endurance I suggest
dosing of 80-160 mg/day. Starting dose, however, generally should be only 40 mg/day until tolerance is
assessed.
While it's not required and telmisartan users in general do not do so, when using this drug I suggest
supplementing with oleuropein 200-400 mg/day and Vitamin D 5000 IU/day. These are to reduce or
perhaps eliminate two activities of telmisartan that I would not consider desirable for physique or
performance enhancement, though they add to its medical use.