China (Mainland)
Tetracaine HCl Topical skin anesthesia raw materials CAS NO.136-47-0
- FOB Price: USD: 50.00-50.00 /Metric Ton Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: T/T,MoneyGram
- Available Specifications:
10(10-20)Metric Ton
- Product Details
Keywords
- Tetracaine HCl
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Quick Details
- ProName: Tetracaine HCl Topical skin anesthesia...
- CasNo: 136-47-0
- Molecular Formula: C26H40O3
- Appearance: White powder
- Application: Tetracaine HCL is synthesized from 4-b...
- DeliveryTime: 7days
- PackAge: Foil bag
- ProductionCapacity: 50000 Kilogram/Week
- Purity: 99
- Storage: Placed in a cool place
- LimitNum: 1 Gram
- Moisture Content: 0.001
- Impurity: 0.001
Superiority
Tetracaine HCl
Product Name Tetracaine HCl Powder
CAS Registry Number 136-47-0
EINECS 205-248-5
Molecular Formula C15H25ClN2O2
Molecular Weight 300.82
Purity 99%
Grade Pharmaceutical Grade
Appearance White cystalline powder
Details
Tetracaine HCl
Product Name Tetracaine HCl Powder
CAS Registry Number 136-47-0
EINECS 205-248-5
Molecular Formula C15H25ClN2O2
Molecular Weight 300.82
Purity 99%
Grade Pharmaceutical Grade
Appearance White cystalline powder
Tetracaine HCL is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine, also known as Amethocalne, Dlcalne, Pontocaine, Decicaine, is a kind of Local Anesthetic. It is highly soluable in Non-polar solvent, and combines with Plasma protein by 85%.
Tetracaine takes effect very fast. It just needs 1-2 min. Usually, its half life is 5-10 min. And it can lasts for 20 ~ 40min.
It is widely used as pain-killer in Mucosal surface anesthesia, Conduction anesthesia, Epidural anesthesia, Spinal anesthesia, Ophthalmic topical anesthesia and so on.
Tetracaine is more efficient than Procaine. It is 10-15 times more effective than it.
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
