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CAS NO.89778-27-8
USP(10-100)GramUSP(101-1000)Gram
Anti Estrogen Steroid Powder Toremifene Citrate For Anti Cancer
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CAS |
89778-27-8 |
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MF |
C26H28ClNO·C6H8O7 |
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MW |
598.09 |
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Assay |
97.0%~103.0% |
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Appearance |
White crystalline powder |
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Suitable for |
adult |
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Certification |
ISO 9001, USP, BP |
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Standard |
USP |
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Usage |
Originally developed to fight breast cancer, bodybuilders have used Fareston to successfully fight gynocomastia caused when testosterone converts to estrogen in the body and men grow breasts. |
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Packing |
Discreet packing ways as your requirement, 100% go through |
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Storage |
Store in cool and dry area and keep away from direct sunlight |
Description:
Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body.
Toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
Toremifene has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body. As a layman explanation.
Toremifene pretends to be a fake Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.
Application:
Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
Effect:
Toremifene Citrate exerts its effects by antagonizing the estrogen receptor in some tissues, and agonizing it in others. In this way, certain estrogenic pathways are activated and others are blockaded. It seems to exert estrogenic effects on blood lipids, reducing LDL and total cholesterol, as well as estrogenic effects on bone, improving density. It would also appear to exert anti-estrogenic effects in breast tissue, displacing the traditional effects of estrogen, effectively helping prevent breast cancer in postmenopausal women.