Superiority
Fluconazole
Chinese name: fluconazole
Synonyms: 2- (2,4-difluorophenyl) -1,3-bis (1H-1,2,4-triazol-1-yl) -2-propanol; fluconazole; (1, 4-difluorophenyl) -Α- (1H-1,2,4-triazol-1-ylmethyl) -1H-1,2,4-triazole (1, 4-difluorophenyl) -1,3-bis (1H-1,2,4-triazol-1-yl) -2-propanol; ; Fluconazole-D4
English name: Fluconazole
FLENONAZOLE-D4; FLUCONAZOLE-D4 (BISMETHYLENE-D4); diflucan; 2,4-DIFLUORO-ALPHA, ALPHA-1-BIS (1H-1,2,4-TRIAZOL-1-YLMETHYL) BENZYL ALCOHOL ; 2,4-DIFLUOROPHENYL-A- (1H-1,2,4-TRIAZOL-1-YLMETHYL) BENZYL ALCOHOL; TRANZOL-1-YLMETHYL) -1H-1,2,4-TRIAZOL-1-ETHANOL; alpha- (2,4-difluorophenyl) -alpha- (1h-1,2,4-triazol-1-ylmethyl) -1,2,4-triazole-1-ethanol
CAS Number: 86386-73-4
Molecular formula: C13H12F2N6O
Molecular weight: 306.27
EINECS number: 200-659-6
Melting point 138-140 ° C
Storage conditions -20 ° C
Solubility DMSO: 5 mg / mL
Details
Fluconazole
Chinese name: fluconazole
Synonyms: 2- (2,4-difluorophenyl) -1,3-bis (1H-1,2,4-triazol-1-yl) -2-propanol; fluconazole; (1, 4-difluorophenyl) -Α- (1H-1,2,4-triazol-1-ylmethyl) -1H-1,2,4-triazole (1, 4-difluorophenyl) -1,3-bis (1H-1,2,4-triazol-1-yl) -2-propanol; ; Fluconazole-D4
English name: Fluconazole
FLENONAZOLE-D4; FLUCONAZOLE-D4 (BISMETHYLENE-D4); diflucan; 2,4-DIFLUORO-ALPHA, ALPHA-1-BIS (1H-1,2,4-TRIAZOL-1-YLMETHYL) BENZYL ALCOHOL ; 2,4-DIFLUOROPHENYL-A- (1H-1,2,4-TRIAZOL-1-YLMETHYL) BENZYL ALCOHOL; TRANZOL-1-YLMETHYL) -1H-1,2,4-TRIAZOL-1-ETHANOL; alpha- (2,4-difluorophenyl) -alpha- (1h-1,2,4-triazol-1-ylmethyl) -1,2,4-triazole-1-ethanol
CAS Number: 86386-73-4
Molecular formula: C13H12F2N6O
Molecular weight: 306.27
EINECS number: 200-659-6
Melting point 138-140 ° C
Storage conditions -20 ° C
Solubility DMSO: 5 mg / mL
Form solid
Chemical properties of white to yellow and white crystalline powder, slightly smell, bitter taste. Soluble in glacial acetic acid, methanol or ethanol, insoluble in water, insoluble in ether, melting point 137 ~ 141.6 ℃, or melting point of 138 ~ 140 ℃ (from ethyl acetate - hexane).
Use of fluorotriazole broad-spectrum antifungal, antibacterial spectrum and ketoconazole similar, long-term, effective for deep infection fungal drugs, anti-fungal effect, good oral absorption. Mainly used for candidiasis and cryptococcal disease, cancer patients with oropharyngeal candidiasis is also effective.
US Pfizer listed a new generation of antifungal drugs, the white ball and Cryptococcus has a high antibacterial activity.
Use of fluconazole This is fluoxazole for the fluorotriazole antifungal, antibacterial spectrum and ketoconazole similar to the antibacterial activity than ketoconazole strong, mainly used as fluconazole fluconazole injection of raw materials.
Use This product is fluorotriazole antifungal, antibacterial spectrum and ketoconazole similar to the antibacterial activity than ketoconazole strong. Its mechanism of action is to inhibit the fungal cell membrane essential ingredients ergosterol synthase, ergosterol synthesis blocked, destruction of fungal cell wall integrity, inhibit its growth and reproduction. This product is Candida albicans, the size of spores, Cryptococcus neoformans, epidermophyton and capsular histoplasmosis, etc. are strong antibacterial live Tian.
Use is the third generation of imidazole antifungal drugs
KG Pharmaceutical grade 99% powdered white 25 kg / plastic drum
China (Mainland)