Superiority
Phenacetin
CAS 62-44-2
It is also called acetophenetidins. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in
ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation
Details
Phenacetin
CAS 62-44-2
It is also called acetophenetidins. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in
ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation
reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever,
headache, neuralgia and other drugs as a compound agent.
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin,
low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic
effect. Because the enzyme inhibitor make phenacetins not be converted into paracetamol, still showed
obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The
mild phenacetisns analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid
coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic
analgesic. This product is also a component of the APC tablet.
3.Product Application:
Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetis has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treatrheumatoid arthritis (subacute type) and intercostal neuralgia.
4.Function:
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin,
low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic
effect. Because the enzyme inhibitor make phenacetins-Acetate not be converted into paracetamol, still showed
obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The
mild phenacetins-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid
coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
China (Mainland)