Superiority
5-Fluorouracil
Common name: fluorouracil fluorouracil
Chemical Name: 5-Fluoro-2,4 (1H, 3H) -pyrimidinedione
Chinese name: 5-fluorouracil
Chinese alias: 2,4-dihydroxy-5-fluoropyrimidine; 5-FU; 5-fluoro-2,4 (1H, 3H)
English name: 5-Fluorouracil
English alias: 2,4-Dihydroxy-5-fluoropyrimidine; 5-FU; 5-Fluoro-2,4 (1H, 3H)
CAS number: 51-21-8
Molecular formula: C4H3FN2O2
Molecular weight: 130.08
MDL number: MFCD00006018
Beilstein no. 127172
EC number: 200-085-6
Traits description: white powder
Melting point: 282-286 ° C (dec.) (Lit.)
Uses: Uses: A potent anti-tumor agent that consumes intracellular dTTP pools by inhibiting thymidylate synthase, affecting pyrimidine synthesis, 5-FU being metabolized to ribonucleotides and deoxyribonucleotides and injected To RNA and DNA. Treatment of cells with 5-FU results in accumulation of cells in S phase, which has been shown to induce p53-dependent apoptosis.
Nucleic acid metabolism, rice, wheat ear differentiation, genetic metabolism, plant growth and development.
China (Mainland)