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CAS NO.330784-47-9
Enterprise Standard(10-100)GramEnterprise Standard(101-1000)Gram
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1)Standard: Enterprise Standard
2)All Purity≥99%
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Top Quality Male Sex Enhancement Powder Avanafil For ED
Product Name |
Avanafil |
CAS |
330784-47-9 |
MF |
C23H26ClN7O3 |
MW |
483.95 |
Purity |
99% |
Appearance |
White to Off-White Cyrstalline Solid |
Certification |
ISO 9001, USP, BP
|
Grade |
Pharma Grade |
Standard |
Enterprise Standard |
Usage |
Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. |
Packing |
Discreet packing ways as your requirement, 100% go through |
Storage |
Store in cool and dry area and keep away from direct sunlight |
Specification:
Test Items | Specification |
Test Results |
|
Description | White or off-white crystalline powder |
Off-white crystalline powder |
|
Specific rotation | -56°~-60° |
-58.2° |
|
Identification | IR | Matches with working standard | Complies |
HPLC | |||
Solubility |
Freely soluble in chloroform and in alcohol; Very slightly soluble in water |
Conform | |
Heavy metals | ≤10ppm |
<10ppm |
|
Water | ≤0.3% |
0.22% |
|
Residue on ignition | ≤0.1% |
0.05% |
|
Relative material | Maximum impurities≤0.5% |
0.36% |
|
Total impurities≤1.0% |
0.52% |
||
Assay | 98.5~101.0% |
99.68% |
|
Conclusion |
The specification conform with Enterprise standard |
Description:
Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than. The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .
Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor inducedand other.
Application:
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarilyin the corpus cavernosum penis, as well as the retina. Other similar drugs are , tadalafil and vardenafil. The advantageof avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbedquickly, reaching a maximum concentration in about 30-45 minutes. About two thirds of participants were able to engage in sexual activity within 15 minutes.
Usage: