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CAS NO.27262-48-2
Enterprise standard(10-100)GramEnterprise standard(101-1000)Gram
1, High quality with competitive price
1)Standard: Enterprise Standard
2)All Purity≥99%
3)We are manufacturer and can provide high quality products with factory price.
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1)Parcel can be sent out in 24 hours after payment. Tracking number available
2)Secure and discreet shipment. Various transportation methods for your choice.
3)Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3, We have clients throughout the world
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3)High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.
99% Purity Local Anesthetic Levobupivacaine Hydrochloride For Pain Killer
Chemical Name |
(2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride |
Product Name |
Levobupivacaine hydrochloride |
CAS |
27262-48-2 |
MF |
C18H29ClN2O |
MW |
324.88873 |
EINECS |
245-957-7 |
Purity |
99% |
Appearance |
white powder |
Certification |
GMP,ISO9001,USP,BP |
Standard |
enterprise standard |
Usage |
Levobupivacaine is amide local anesthetics, mainly for surgical epidural anesthesia |
Description:
Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.
Application:
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
COA:
Test Items |
Specification |
Test Results |
Description |
White or almost white crystalline powder |
White crystalline powder |
Melting Point |
191.0~193.0ºC |
192ºC |
Loss of drying |
≤1.0% |
0.5% |
Heavy Metal |
≤20ppm |
15ppm |
TLC |
Only one spot |
Only one spot |
Assay |
≥99.5% |
99.91% |
Conclusion |
It complies with the USP 32. |