Jinan Jiage biological technology co., LTD(expird)
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Country: 
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Business Type:Trading Company
CAS NO.145-13-1
USP(10-100)Metric TonUSP(101-1000)Metric Ton
99% Purity Estrogen Steroid Powder Pregnenolone For Antineoplastic
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Synonym |
DELTA5-PREGNEN-3BETA-OL-20-ONE |
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CAS NO |
145-13-1 |
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MF |
C21H32O2 |
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MW |
316.48 |
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Purity |
99% |
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Appearance |
white to off-white powder |
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Certification |
GMP, ISO 9001, USP, BP |
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Standard |
Enterprise standard |
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Usage |
Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. |
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Packing |
Discreet packing ways as your requirement, 100% go through |
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Storage |
Store in cool and dry area and keep away from direct sunlight |
Description:
Pregnenolone (3¦Â-hydroxypregn-5-en-20-one), also known as P5, is an endogenous steroid hormone. It is the precursor of the progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.
Like other steroids, pregnenolone consists of four interconnected cyclic hydrocarbons. It contains ketone and hydroxyl functional groups, two methyl branches, and a double bond at C5, in the B cyclic hydrocarbon ring. Like many steroid hormones, it is hydrophobic. Its esterified version, pregnenolone sulfate, is water-soluble.
Application:
Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone,mineralocorticoids,
glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.
Specification:
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Test |
Specification |
Result |
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Appearance |
Qualified |
White crystalline powder |
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Melting point |
182~190.5ºC |
180~193ºC |
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Loss on drying |
0.22% |
0.50%max |
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Specific rotation |
+28° |
+27°~+30° |
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Identification(TLC) |
Conform to standard |
Identical with and at least nearly equivalent to the pregnenolone reference standard with reference to integrity, intensity, spot color and RF value, compared to sample FR0025 |
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Related substances (HPLC) |
Any single impurities: 0.30a/a% |
Δ14-pregnenolone: ≤0.3a/a% |
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17-Alpha: ≤0.3a/a% |
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5α/β-pregnenolone≤0.4 a/a% |
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Any single impurity: ≤0.4 a/a% |
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0.64% |
Total impurities: ≤1.0 a/a% |
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Assay (dried basis) |
99.36% |
99.0%min |
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Conclusion |
The test result of the above mentioned product meets the enterprise standard |
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