Superiority
We have a highly qualified and experienced R&D team for research, development, pilot test, commercialized scale production and product registration.
1, A professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
2, Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
3, Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed.
4, Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24 hours.
5, High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, UPS, etc.
Details
Safe Delivery Pharmaceutical Intermediate Dapoxetine Hydrochloride For Erectile Dysfunction
|
Product Name |
Dapoxetine |
|
CAS |
119356-77-3
|
|
MF |
C21H23NO.ClH |
|
MW |
341.88
|
|
Purity |
99.5%
|
|
Appearance |
White crystalline powder |
|
Certification |
GMP, ISO 9001, USP, BP
|
|
Standard |
Enterprise Standard |
|
Grade |
Pharma Grade |
|
Usage |
Treat male premature ejaculation and erectile dysfunction |
|
Storage |
Store in cool and dry area and keep away from direct sunlight
|
|
Delivery Time |
Within 24 hours after your payment |
Description:
Dapoxetine is a new drug that has gained most of the people's interest and it is used as a treatment for premature ejaculation.
Dapoxetine is a selective serotonin reuptake inhibitor and affects the central nervous system reducing the conductivity of the impulses which are transmitted from the penis to the brain during sexual intercourse. The reduction of the conductivity of these impulses allows to control the process of ejaculation and duration of the sexual intercourse.
Also, It improves the psychological condition of the man, reduces diffidence, fear before sexual intercourse, constraint, increases the release of adrenalin, self-appraisal and confidence in the strength. Taking only one tablet of this medicine the man psychologically and physically prepares for the sexual activity and nothing may interfere him to get maximal satisfaction from the long sexual contact.
Application:
Dapoxetine is the first compound developed specially for the treatment of premature ejaculation (PE) in men 1864 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
COA:
|
ITEMS |
STANDARD |
RESULTS |
|
Characteristics |
White or almost white crystalline powder |
White crystalline powder |
|
Melting point |
175.0~177.0ºC |
174.0~179.0ºC |
|
Specific rotatlon |
+128°±3(C=1,CH3OH) |
+128°±3(C=1,CH3OH) |
|
Loss on drying |
≤0.5% |
0.32% |
|
Heavy metals |
0ppm |
0ppm |
|
Relative substance |
≤0.1%
Total impurity |
0.07% |
|
Assay(on drled basis) |
≥99.5% |
99.61% |
|
Conclusion |
It complies to prescrlbed enterprise standard |
Usage:
Current treatment approaches for PE include off-label use of the selective serotonin reuptake inhibitors such as fluoxetine and paroxetine, clomipramine, and topical anesthetics.Dapoxetine is a new fast-acting serotonin transporter inhibitor that is under FDA review for the treatment of premature ejaculation.Dapoxetine would be the first drug specifically indicated for this disorder.
Advantage:
We have a highly qualified and experienced R&D team for research, development, pilot test, commercialized scale production and product registration.
1, a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
2, Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
3, Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed.
4, Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
5, High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, UPS, etc.
China (Mainland)