Superiority
Levofloxacin
Chinese name: levofloxacin
Chinese Synonyms: (-) 9-Fluoro-2,3-dihydro-3-methyl-10- (4-methyl-1-piperazinyl) Levofloxacin levofloxacin levofloxacin levofloxacin hydrochloride 3-DE] - [1,4] benzoxazine-6-carboxylic acid Salt; levofloxacin 99%
English name: Levofloxacin hydrochloride
English Synonyms: (s) -ofloxacin; 7h-pyrido (1,2,3-de) -1,4-benzoxazine-6-carboxylicacid, 2,3- dihydro- 9-fluoro-3-m; (4-methyl-1-piperazinyl) -7-oxo; LEVOFLOXACIN HCL; LEVOFLOXACIN HEMIHYDRATE; (3s) -9-fluoro-2,3- -methyl-1-piperazinyl) -7-oxo-7h-pyrido [1,2,3-de] -1,4-benzoxazine-6-carboxylic acid monohydrochloride; Levofloxacin base
CAS number: 100986-85-4
Molecular formula: C18H20FN3O4
Molecular weight: 361.37
Chemical properties Levofloxacin is ofloxacin L-body, as hemihydrate. Its solubility in water is 10 times that of the latter. Obtained from ethanol - ether needle crystallization, mp 225-227 ° C. [α] D 23-76.9 ° (C = 0.385, 0.5 mol / L sodium hydroxide solution). Acute toxicity LD50 male and female mice, male and female rats (mg / kg): 1881,1803,1478,1507 orally.
Use Levofloxacin has excellent in vitro activity, less toxic side effects than ofloxacin, safety and good pharmacokinetic properties. It can be widely used in oral or parenteral broad-spectrum fluoroquinolone antibacterials for respiratory infections, gynecological diseases, skin and soft tissue infections, surgical infections, biliary tract infections, sexually transmitted diseases and ear infections.
Use Mainly used in the manufacture of various types of levofloxacin capsules, tablets and other antibacterial agents
Use for the synthesis of antibiotics, used to treat respiratory tract, urinary tract and skin tissue infections
Use for the synthesis of antibiotics, the treatment of various bacterial infections.
China (Mainland)